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Interferon‐alpha‐induced hepatitis C virus clearance restores p53 tumor suppressor more than direct‐acting antivirals

The mechanism why hepatitis C virus (HCV) clearance by direct‐acting antivirals (DAAs) does not eliminate the risk of hepatocellular carcinoma (HCC) among patients with advanced cirrhosis is unclear. Many viral and bacterial infections degrade p53 in favor of cell survival to adapt an endoplasmic re...

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Detalles Bibliográficos
Autores principales: Aydin, Yucel, Chatterjee, Animesh, Chandra, Partha K, Chava, Srinivas, Chen, Weina, Tandon, Anamika, Dash, Asha, Chedid, Milad, Moehlen, Martin W, Regenstein, Frederic, Balart, Luis A, Cohen, Ari, Lu, Hua, Wu, Tong, Dash, Srikanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721446/
https://www.ncbi.nlm.nih.gov/pubmed/29404458
http://dx.doi.org/10.1002/hep4.1025