Sofosbuvir‐based regimens for the treatment of chronic hepatitis C in severe renal dysfunction

Sofosbuvir (SOF) is a nonstructural 5B polymerase inhibitor with activity in all hepatitis C virus (HCV) genotypes and is the backbone of many anti‐HCV drug regimens. SOF is converted into inactive metabolites that undergo renal excretion. Patients with an estimated glomerular filtration rate (eGFR)...

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Detalles Bibliográficos
Autores principales: Cox‐North, Paula, Hawkins, Kelsey L., Rossiter, Sean T., Hawley, Marie N., Bhattacharya, Renuka, Landis, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721450/
https://www.ncbi.nlm.nih.gov/pubmed/29404457
http://dx.doi.org/10.1002/hep4.1035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721450/
https://www.ncbi.nlm.nih.gov/pubmed/29404457
http://dx.doi.org/10.1002/hep4.1035

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