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Sofosbuvir‐based regimens for the treatment of chronic hepatitis C in severe renal dysfunction
Sofosbuvir (SOF) is a nonstructural 5B polymerase inhibitor with activity in all hepatitis C virus (HCV) genotypes and is the backbone of many anti‐HCV drug regimens. SOF is converted into inactive metabolites that undergo renal excretion. Patients with an estimated glomerular filtration rate (eGFR)...
Autores principales: | Cox‐North, Paula, Hawkins, Kelsey L., Rossiter, Sean T., Hawley, Marie N., Bhattacharya, Renuka, Landis, Charles S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721450/ https://www.ncbi.nlm.nih.gov/pubmed/29404457 http://dx.doi.org/10.1002/hep4.1035 |
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