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Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1

BACKGROUND: The cell-surface heparan sulfate proteoglycan syndecan-1 is important for tumor cell proliferation, migration, and cell cycle regulation in a broad spectrum of malignancies. Syndecan-1, however, also translocates to the cell nucleus, where it might regulate various molecular functions. R...

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Detalles Bibliográficos
Autores principales: Szatmári, Tünde, Mundt, Filip, Kumar-Singh, Ashish, Möbus, Lena, Ötvös, Rita, Hjerpe, Anders, Dobra, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721467/
https://www.ncbi.nlm.nih.gov/pubmed/29216821
http://dx.doi.org/10.1186/s12860-017-0150-z