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Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel

BACKGROUND: Docetaxel-based chemotherapy failure in advanced prostate carcinoma has partly been attributed to the resistance of prostate cancer (PC) cells to docetaxel-induced apoptosis. Hence, there is an urgent need to identify mechanisms of docetaxel chemoresistance and to develop new combination...

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Detalles Bibliográficos
Autores principales: Yang, Zhan, Chen, Jin-Suo, Wen, Jin-Kun, Gao, Hai-Tao, Zheng, Bin, Qu, Chang-Bao, Liu, Kai-Long, Zhang, Man-Li, Gu, Jun-Fei, Li, Jing-Dong, Zhang, Yan-Ping, Li, Wei, Wang, Xiao-Lu, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721613/
https://www.ncbi.nlm.nih.gov/pubmed/29216925
http://dx.doi.org/10.1186/s13046-017-0649-3