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VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes

BACKGROUND: In addition to activated T cells, the immune checkpoint inhibitor “V domain-containing Ig suppressor of T-cell activation” (VISTA) is expressed by myeloid cell types, including macrophages and neutrophils. The importance of VISTA expression by myeloid cells to antibody-induced arthritis...

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Detalles Bibliográficos
Autores principales: Ceeraz, Sabrina, Eszterhas, Susan K., Sergent, Petra A., Armstrong, David A., Ashare, Alix, Broughton, Thomas, Wang, Li, Pechenick, Dov, Burns, Christopher M., Noelle, Randolph J., Vincenti, Matthew P., Fava, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721690/
https://www.ncbi.nlm.nih.gov/pubmed/29216931
http://dx.doi.org/10.1186/s13075-017-1474-y