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miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3β-involved Wnt/β-catenin signaling

BACKGROUND: Hepatocellular carcinoma (HCC) remains one of the most lethal cancers. MicroRNA-155 (miR-155) and collagen triple helix repeat containing 1 (CTHRC1) were found to be involved in hepatocarcinogenesis, but their detailed functions in HCC are unclear. Here, we aimed to investigate the under...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Wang, Dongdong, Zhao, Xiongqi, Cao, Jun, Zhao, Yingpeng, Wang, Fan, Bai, Jianhua, Luo, Ding, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721693/
https://www.ncbi.nlm.nih.gov/pubmed/29234238
http://dx.doi.org/10.1186/s12935-017-0469-8