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miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3β-involved Wnt/β-catenin signaling
BACKGROUND: Hepatocellular carcinoma (HCC) remains one of the most lethal cancers. MicroRNA-155 (miR-155) and collagen triple helix repeat containing 1 (CTHRC1) were found to be involved in hepatocarcinogenesis, but their detailed functions in HCC are unclear. Here, we aimed to investigate the under...
Autores principales: | Chen, Gang, Wang, Dongdong, Zhao, Xiongqi, Cao, Jun, Zhao, Yingpeng, Wang, Fan, Bai, Jianhua, Luo, Ding, Li, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721693/ https://www.ncbi.nlm.nih.gov/pubmed/29234238 http://dx.doi.org/10.1186/s12935-017-0469-8 |
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