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Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease

BACKGROUND: Genome‐wide association studies identified ADAMTS7 as a risk locus for coronary artery disease (CAD). Functional studies suggest that ADAMTS7 may promote cellular processes in atherosclerosis. We sought to examine the association between genetic variation at ADAMTS7 and measures of ather...

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Detalles Bibliográficos
Autores principales: Chan, Kenneth, Pu, Xiangyuan, Sandesara, Pratik, Poston, Robin N., Simpson, Iain A., Quyyumi, Arshed A., Ye, Shu, Patel, Riyaz S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721775/
https://www.ncbi.nlm.nih.gov/pubmed/29089340
http://dx.doi.org/10.1161/JAHA.117.006928