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Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca(2+)/Calmodulin‐Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development

BACKGROUND: Congenital heart defects are the most common birth defects worldwide. Although defective Notch signaling is the major cause of mouse embryonic death from cardiovascular defects, how Notch signaling is regulated during embryonic vasculogenesis and heart development is poorly understood. M...

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Detalles Bibliográficos
Autores principales: Chakravarti, Bandana, Yang, Jianqi, Ahlers‐Dannen, Katelin E., Luo, Zili, Flaherty, Heather A., Meyerholz, David K., Anderson, Mark E., Fisher, Rory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721783/
https://www.ncbi.nlm.nih.gov/pubmed/29079565
http://dx.doi.org/10.1161/JAHA.117.007038