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SDF‐1α (Stromal Cell‐Derived Factor 1α) Induces Cardiac Fibroblasts, Renal Microvascular Smooth Muscle Cells, and Glomerular Mesangial Cells to Proliferate, Cause Hypertrophy, and Produce Collagen

BACKGROUND: Activated cardiac fibroblasts (CFs), preglomerular vascular smooth muscle cells (PGVSMCs), and glomerular mesangial cells (GMCs) proliferate, cause hypertrophy, and produce collagen; in this way, activated CFs contribute to cardiac fibrosis, and activated PGVSMCs and GMCs promote renal f...

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Detalles Bibliográficos
Autores principales: Jackson, Edwin K., Zhang, Yumeng, Gillespie, Delbert D., Zhu, Xiao, Cheng, Dongmei, Jackson, Travis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721794/
https://www.ncbi.nlm.nih.gov/pubmed/29114002
http://dx.doi.org/10.1161/JAHA.117.007253