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The Role of Obesity, Type 2 Diabetes, and Metabolic Factors in Pancreatic Cancer: A Mendelian Randomization Study

BACKGROUND: Risk factors for pancreatic cancer include a cluster of metabolic conditions such as obesity, hypertension, dyslipidemia, insulin resistance, and type 2 diabetes. Given that these risk factors are correlated, separating out causal from confounded effects is challenging. Mendelian randomi...

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Detalles Bibliográficos
Autores principales: Carreras-Torres, Robert, Johansson, Mattias, Gaborieau, Valerie, Haycock, Philip C., Wade, Kaitlin H., Relton, Caroline L., Martin, Richard M., Davey Smith, George, Brennan, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721813/
https://www.ncbi.nlm.nih.gov/pubmed/28954281
http://dx.doi.org/10.1093/jnci/djx012