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Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53‐Dependent Apoptosis

BACKGROUND: Cardiomyocytes differentiated from human pluripotent stem cells can serve as an unexhausted source for a cellular cardiac disease model. Although small molecule–mediated cardiomyocyte differentiation methods have been established, the differentiation efficiency is relatively unsatisfacto...

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Detalles Bibliográficos
Autores principales: Qiu, Xiao‐Xu, Liu, Yang, Zhang, Yi‐Fan, Guan, Ya‐Na, Jia, Qian‐Qian, Wang, Chen, Liang, He, Li, Yong‐Qin, Yang, Huang‐Tian, Qin, Yong‐Wen, Huang, Shuang, Zhao, Xian‐Xian, Jing, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721819/
https://www.ncbi.nlm.nih.gov/pubmed/28971953
http://dx.doi.org/10.1161/JAHA.116.005295