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Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53‐Dependent Apoptosis
BACKGROUND: Cardiomyocytes differentiated from human pluripotent stem cells can serve as an unexhausted source for a cellular cardiac disease model. Although small molecule–mediated cardiomyocyte differentiation methods have been established, the differentiation efficiency is relatively unsatisfacto...
Autores principales: | Qiu, Xiao‐Xu, Liu, Yang, Zhang, Yi‐Fan, Guan, Ya‐Na, Jia, Qian‐Qian, Wang, Chen, Liang, He, Li, Yong‐Qin, Yang, Huang‐Tian, Qin, Yong‐Wen, Huang, Shuang, Zhao, Xian‐Xian, Jing, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721819/ https://www.ncbi.nlm.nih.gov/pubmed/28971953 http://dx.doi.org/10.1161/JAHA.116.005295 |
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