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Interleukin 22 Promotes Blood Pressure Elevation and Endothelial Dysfunction in Angiotensin II–Treated Mice

BACKGROUND: CD4+ T helper (Th) cells, including Th1, Th2, and Th17 cells, play critical roles in angiotensin II–induced hypertension. Th22 cells, a novel subset of Th cells, take part in cardiovascular diseases by producing IL‐22 (interleukin 22). This study aimed to investigate whether IL‐22 is inv...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Ji, Qingwei, Liu, Jianfang, Liu, Ling, Huang, Ying, Shi, Ying, Shi, Lei, Wang, Menglong, Liu, Mengling, Feng, Ying, Jiang, Huimin, Xu, Yao, Wang, Zhen, Song, Junlong, Lin, Yingzhong, Wan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721831/
https://www.ncbi.nlm.nih.gov/pubmed/28974499
http://dx.doi.org/10.1161/JAHA.117.005875