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Endoplasmic Reticulum Stress Is Associated With Autophagy and Cardiomyocyte Remodeling in Experimental and Human Atrial Fibrillation

BACKGROUND: Derailment of proteostasis, the homeostasis of production, function, and breakdown of proteins, contributes importantly to the self‐perpetuating nature of atrial fibrillation (AF), the most common heart rhythm disorder in humans. Autophagy plays an important role in proteostasis by degra...

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Detalles Bibliográficos
Autores principales: Wiersma, Marit, Meijering, Roelien A. M., Qi, Xiao‐Yan, Zhang, Deli, Liu, Tao, Hoogstra‐Berends, Femke, Sibon, Ody C. M., Henning, Robert H., Nattel, Stanley, Brundel, Bianca J. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721854/
https://www.ncbi.nlm.nih.gov/pubmed/29066441
http://dx.doi.org/10.1161/JAHA.117.006458