Prolyl 4‐Hydroxylase Domain Protein 3 Overexpression Improved Obstructive Sleep Apnea—Induced Cardiac Perivascular Fibrosis Partially by Suppressing Endothelial‐to‐Mesenchymal Transition

BACKGROUND: Intermittent hypoxia (IH) induced by obstructive sleep apnea is the key factor involved in cardiovascular fibrosis. Under persistent hypoxia condition, endothelial cells respond by endothelial‐to‐mesenchymal transition (EndMT), which is associated with cardiovascular fibrosis. Prolyl 4‐h...

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Detalles Bibliográficos
Autores principales: Zhang, Guang‐hao, Yu, Fu‐chao, Li, Yang, Wei, Qin, Song, Song‐song, Zhou, Fang‐ping, Tong, Jia‐yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721870/
https://www.ncbi.nlm.nih.gov/pubmed/29051216
http://dx.doi.org/10.1161/JAHA.117.006680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721870/
https://www.ncbi.nlm.nih.gov/pubmed/29051216
http://dx.doi.org/10.1161/JAHA.117.006680

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