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Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways

BACKGROUND: During high sodium intake, the renin‐angiotensin‐aldosterone system is downregulated and nitric oxide signaling is upregulated in order to remain in sodium balance. Recently, we showed that collecting duct nitric oxide synthase 1β is critical for fluid‐electrolyte balance and subsequentl...

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Detalles Bibliográficos
Autores principales: Hyndman, Kelly A., Mironova, Elena V., Giani, Jorge F., Dugas, Courtney, Collins, Jessika, McDonough, Alicia A., Stockand, James D., Pollock, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721879/
https://www.ncbi.nlm.nih.gov/pubmed/29066445
http://dx.doi.org/10.1161/JAHA.117.006896