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Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways
BACKGROUND: During high sodium intake, the renin‐angiotensin‐aldosterone system is downregulated and nitric oxide signaling is upregulated in order to remain in sodium balance. Recently, we showed that collecting duct nitric oxide synthase 1β is critical for fluid‐electrolyte balance and subsequentl...
Autores principales: | Hyndman, Kelly A., Mironova, Elena V., Giani, Jorge F., Dugas, Courtney, Collins, Jessika, McDonough, Alicia A., Stockand, James D., Pollock, Jennifer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721879/ https://www.ncbi.nlm.nih.gov/pubmed/29066445 http://dx.doi.org/10.1161/JAHA.117.006896 |
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