Cargando…

Single-cell studies of IFN-β promoter activation by wild-type and NS1-defective influenza A viruses

Deletion or truncation of NS1, the principal IFN antagonist of influenza viruses, leads to increased IFN induction during influenza virus infection. We have studied activation of the IFN induction cascade by both wild-type and NS1-defective viruses at the single-cell level using a cell line expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Killip, M. J, Jackson, D, Pérez-Cidoncha, M, Fodor, E, Randall, R. E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721924/
https://www.ncbi.nlm.nih.gov/pubmed/27983470
http://dx.doi.org/10.1099/jgv.0.000687