Cargando…

Single-cell studies of IFN-β promoter activation by wild-type and NS1-defective influenza A viruses

Deletion or truncation of NS1, the principal IFN antagonist of influenza viruses, leads to increased IFN induction during influenza virus infection. We have studied activation of the IFN induction cascade by both wild-type and NS1-defective viruses at the single-cell level using a cell line expressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Killip, M. J, Jackson, D, Pérez-Cidoncha, M, Fodor, E, Randall, R. E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2017
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721924/ https://www.ncbi.nlm.nih.gov/pubmed/27983470 http://dx.doi.org/10.1099/jgv.0.000687

Ejemplares similares

Generation of Replication-Proficient Influenza Virus NS1 Point Mutants with Interferon-Hyperinducer Phenotype
por: Pérez-Cidoncha, Maite, et al.
Publicado: (2014)

Failure to activate the IFN-β promoter by a paramyxovirus lacking an interferon antagonist()
por: Killip, M.J., et al.
Publicado: (2011)

Influenza virus activation of the interferon system
por: Killip, Marian J., et al.
Publicado: (2015)

Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling
por: Pachler, Karin, et al.
Publicado: (2011)

Human interactome of the influenza B virus NS1 protein
por: Patzina, Corinna, et al.
Publicado: (2017)

An Unbiased Genetic Screen Reveals the Polygenic Nature of the Influenza Virus Anti-Interferon Response
por: Pérez-Cidoncha, Maite, et al.
Publicado: (2014)

Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export
por: Killip, Marian J., et al.
Publicado: (2014)

Nucleolar localization of influenza A NS1: striking differences between mammalian and avian cells
por: Volmer, Romain, et al.
Publicado: (2010)

The Human Interferon-Induced MxA Protein Inhibits Early Stages of Influenza A Virus Infection by Retaining the Incoming Viral Genome in the Cytoplasm
por: Xiao, Han, et al.
Publicado: (2013)

The influenza A virus NS genome segment displays lineage-specific patterns in predicted RNA secondary structure
por: Vasin, A. V., et al.
Publicado: (2016)

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein
por: Rajsbaum, Ricardo, et al.
Publicado: (2012)

Changes in RNA secondary structure affect NS1 protein expression during early stage influenza virus infection
por: Baranovskaya, Irina, et al.
Publicado: (2019)

The wild side of plant microbiomes
por: Pérez-Jaramillo, Juan E., et al.
Publicado: (2018)

A conserved predicted pseudoknot in the NS2A-encoding sequence of West Nile and Japanese encephalitis flaviviruses suggests NS1' may derive from ribosomal frameshifting
por: Firth, Andrew E, et al.
Publicado: (2009)

The Comparison Between the Mutated HuIFN-β 27-101 and the Wild Type Interferon β: the Comprehensive In Silico Study to Evaluate the Effect of Mutations on IFN-β
por: Balkhi, Sayed Sharif, et al.
Publicado: (2019)

Activation of the beta interferon promoter by paramyxoviruses in the absence of virus protein synthesis
por: Killip, M. J., et al.
Publicado: (2012)

HCV NS3 Blocking Effect on IFN Induced ISGs Like Viperin and IL28 With and Without NS4A
por: Khanlari, Zahra, et al.
Publicado: (2014)

Regulation of IFNα-induced expression of the short ACE2 isoform by ULK1
por: Perez, Ricardo E., et al.
Publicado: (2022)

Circulation of avian influenza viruses in wild birds in Inner Niger Delta, Mali
por: Cappelle, Julien, et al.
Publicado: (2011)

Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma
por: Numata, Yasunao, et al.
Publicado: (2022)

Feline Panleucopenia Virus NS2 Suppresses the Host IFN-β Induction by Disrupting the Interaction between TBK1 and STING
por: Kang, Hongtao, et al.
Publicado: (2017)

Differential inflammasome expression and IL-1β secretion in monocyte-derived dendritic cells differentiated with IL-4 or IFN-α
por: Pontillo, Alessandra, et al.
Publicado: (2013)

Influenza vaccination during pregnancy and risk of selected major structural congenital heart defects, National Birth Defects Prevention Study 2006–2011
por: Palmsten, Kristin, et al.
Publicado: (2022)

Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C
por: Costantino, Angela, et al.
Publicado: (2015)

Retinoic acid-inducible gene 1 (RIG-1) and IFN-β promoter stimulator-1 (IPS-1) significantly down-regulated in the severe coronavirus disease 2019 (COVID-19)
por: Nahavandi-Parizi, Peyman, et al.
Publicado: (2022)

Influenza A virus NS1 protein represses antiviral immune response by hijacking NF-κB to mediate transcription of type III IFN
por: Lee, Meng-Chang, et al.
Publicado: (2022)

The SUMO-interacting motif in NS2 promotes adaptation of avian influenza virus to mammals
por: Sun, Liuke, et al.
Publicado: (2023)

β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling
por: Hillesheim, Andrea, et al.
Publicado: (2014)

Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-β induction
por: Shi, Xibao, et al.
Publicado: (2011)

Diversity of avian influenza A(H5N6) viruses in wild birds in southern China
por: Zhang, Tao, et al.
Publicado: (2020)

Effect of iron overload on furin expression in wild-type and β-thalassemic mice
por: Wichaiyo, Surasak, et al.
Publicado: (2015)

Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion
por: Zheng, Jiangang, et al.
Publicado: (2021)

A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain
por: Kerry, Philip S., et al.
Publicado: (2011)

Context Is Key: Delineating the Unique Functions of IFNα and IFNβ in Disease
por: Fox, Lindsey E., et al.
Publicado: (2020)

Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution
por: Yang, Qing, et al.
Publicado: (2023)

A Closer Look at the NS1 of Influenza Virus
por: Dundon, William G., et al.
Publicado: (2009)

Avian influenza virus NS1: A small protein with diverse and versatile functions
por: Abdelwhab, E M, et al.
Publicado: (2013)

Porcine Deltacoronavirus Accessory Protein NS7a Antagonizes IFN-β Production by Competing With TRAF3 and IRF3 for Binding to IKKε
por: Fang, Puxian, et al.
Publicado: (2020)

Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022
por: Liang, Yuan, et al.
Publicado: (2023)

The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?
por: Barba, Marta, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_chhvdv7sje849dipssdnn66oen