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Potential link between genetic polymorphisms of catechol-O-methyltransferase and dopamine receptors and treatment efficacy of risperidone on schizophrenia

OBJECTIVE: The current study aimed to explore the association of single nucleotide polymorphisms (SNPs) within catechol-O-methyltransferase (COMT) and dopamine receptors with schizophrenia and genetic association with risperidone treatment response. METHODS: A total of 690 schizophrenic patients (ca...

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Detalles Bibliográficos
Autores principales: Han, Jiyang, Li, Yan, Wang, Xumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722007/
https://www.ncbi.nlm.nih.gov/pubmed/29255361
http://dx.doi.org/10.2147/NDT.S148824