Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy

Anti-angiogenesis therapy has shown clinical benefit in patients with high-grade serous ovarian cancer (HGSC), but adaptive resistance rapidly emerges. Thus, approaches to overcome such resistance are needed. We developed the setting of adaptive resistance to anti-VEGF therapy, and performed a serie...

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Detalles Bibliográficos
Autores principales: Lyons, Yasmin A., Pradeep, Sunila, Wu, Sherry Y., Haemmerle, Monika, Hansen, Jean M., Wagner, Michael J., Villar-Prados, Alejandro, Nagaraja, Archana S., Dood, Robert L., Previs, Rebecca A., Hu, Wei, Zhao, Yang, Mak, Duncan H., Xiao, Zhilan, Melendez, Brenda D., Lizee, Gregory A., Mercado-Uribe, Imelda, Baggerly, Keith A., Hwu, Patrick, Liu, Jinsong, Overwijk, Willem W., Coleman, Robert L., Sood, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722500/
https://www.ncbi.nlm.nih.gov/pubmed/29228548
http://dx.doi.org/10.18632/oncotarget.20410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722500/
https://www.ncbi.nlm.nih.gov/pubmed/29228548
http://dx.doi.org/10.18632/oncotarget.20410

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