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1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates arthritic joints through reducing neutrophil infiltration mediated by IL-6/STAT3 and MIP-2 activation

The pathogenesis of rheumatoid arthritis (RA) has been implicated neutrophil extracellular traps (NETs) formation which could generate autoantigen. Neutrophil contributes to initiate and maintain the inflammatory process in the joint. In this study, we show that 1-palmitoyl-2-linoleoyl-3-acetyl-rac-...

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Detalles Bibliográficos
Autores principales: Kim, Young-Jun, Shin, Jae Min, Shin, Su-Hyun, Kim, Joo Heon, Sohn, Ki-Young, Kim, Heung-Jae, Kang, Jong-Koo, Yoon, Sun Young, Kim, Jae Wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722510/
https://www.ncbi.nlm.nih.gov/pubmed/29228558
http://dx.doi.org/10.18632/oncotarget.19384