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Clinical mutational profiling of 1006 lung cancers by next generation sequencing

Analysis of lung adenocarcinomas for actionable mutations has become standard of care. Here, we report our experience using next generation sequencing (NGS) to examine AKT1, BRAF, EGFR, ERBB2, KRAS, NRAS, and PIK3CA genes in 1006 non-small cell lung cancers in a clinical diagnostic setting. NGS demo...

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Detalles Bibliográficos
Autores principales: Illei, Peter B., Belchis, Deborah, Tseng, Li-Hui, Nguyen, Doreen, De Marchi, Federico, Haley, Lisa, Riel, Stacy, Beierl, Katie, Zheng, Gang, Brahmer, Julie R., Askin, Frederic B., Gocke, Christopher D., Eshleman, James R., Forde, Patrick M., Lin, Ming-Tseh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722514/
https://www.ncbi.nlm.nih.gov/pubmed/29228562
http://dx.doi.org/10.18632/oncotarget.18042