Keratin 8 reduces colonic permeability and maintains gut microbiota homeostasis, protecting against colitis and colitis-associated tumorigenesis

Keratin 8 (CK8) is the major component of the intermediate filaments of simple or single-layered epithelia. Gene targeting mice model suggest that CK8 is involved in colonic active ion transport, colorectal hyperplasia and inflammation. In the present study, we found that CK8 is downregulated in the...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Liu, En-Dong, Meng, Yun-Xiao, Dong, Xiao-Ming, Bi, Ya-Lan, Wu, Huan-Wen, Jin, Yan-Chao, Zhao, Ke, Li, Jian-Jie, Yu, Miao, Zhan, Yi-Qun, Chen, Hui, Ge, Chang-Hui, Yang, Xiao-Ming, Li, Chang-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722522/
https://www.ncbi.nlm.nih.gov/pubmed/29228570
http://dx.doi.org/10.18632/oncotarget.18241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722522/
https://www.ncbi.nlm.nih.gov/pubmed/29228570
http://dx.doi.org/10.18632/oncotarget.18241

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