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Microfluidic hydrodynamic focusing synthesis of polymer-lipid nanoparticles for siRNA delivery
Small interfering RNAs (siRNAs) are promising as therapeutics for intractable diseases such as cancer. However, efficient and safe delivery of siRNAs in vivo remains a challenge. Polymer-lipid hybrid nanoparticles (P/LNPs) have been evaluated for therapeutic delivery of siRNA. In this study, a micro...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722526/ https://www.ncbi.nlm.nih.gov/pubmed/29228574 http://dx.doi.org/10.18632/oncotarget.18281 |