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Microfluidic hydrodynamic focusing synthesis of polymer-lipid nanoparticles for siRNA delivery

Small interfering RNAs (siRNAs) are promising as therapeutics for intractable diseases such as cancer. However, efficient and safe delivery of siRNAs in vivo remains a challenge. Polymer-lipid hybrid nanoparticles (P/LNPs) have been evaluated for therapeutic delivery of siRNA. In this study, a micro...

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Detalles Bibliográficos
Autores principales:	Huang, Xueqin, Lee, Robert J., Qi, Yuhang, Li, Yujing, Lu, Jiahui, Meng, Qingfan, Teng, Lesheng, Xie, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722526/ https://www.ncbi.nlm.nih.gov/pubmed/29228574 http://dx.doi.org/10.18632/oncotarget.18281

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