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Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabetes mellitus with macrovascular complications

This study investigated the role of the JAK2/STAT3/SOCS pathway in type 2 diabetes mellitus (T2DM) and macrovascular complications (DV) (T2DM+DV) conditions. Human umbilical vein endothelial cells (HUVECs) were co-cultured with human monocytes (THP-1) and exposed to peripheral blood sera from 30 T2D...

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Detalles Bibliográficos
Autores principales: Yang, Mengxue, Tian, Mei, Zhang, Xuan, Xu, Jie, Yang, Bo, Yu, Jie, Li, Fengping, Li, Ya, Li, Sicheng, Li, Xianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722537/
https://www.ncbi.nlm.nih.gov/pubmed/29228585
http://dx.doi.org/10.18632/oncotarget.18555