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Role of melatonin combined with exercise as a switch-like regulator for circadian behavior in advanced osteoarthritic knee

Here, we show the role of melatonin combined with or without exercise as a determinant of multicellular behavior in osteoarthritis. We address the relationship between the molecular components governing local circadian clock and changes in the osteoarthritic musculoskeletal axis. Melatonin was injec...

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Detalles Bibliográficos
Autores principales: Hong, Yunkyung, Kim, Hyunsoo, Lee, Seunghoon, Jin, Yunho, Choi, Jeonghyun, Lee, Sang-Rae, Chang, Kyu-Tae, Hong, Yonggeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722591/
https://www.ncbi.nlm.nih.gov/pubmed/29228639
http://dx.doi.org/10.18632/oncotarget.19276