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A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size

The Hippo/Yki and RB/E2F pathways both regulate tissue growth by affecting cell proliferation and survival, but interactions between these parallel control systems are poorly defined. In this study, we demonstrate that interaction between Drosophila E2F1 and Sd disrupts Yki/Sd complex formation and...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Pei, Chunli, Wang, Xi, Xiang, Jinyi, Sun, Bao-Fa, Cheng, Yongsheng, Qi, Xiaolong, Marchetti, Marco, Xu, Jia-Wei, Sun, Ying-Pu, Edgar, Bruce A., Yuan, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722641/
https://www.ncbi.nlm.nih.gov/pubmed/29207260
http://dx.doi.org/10.1016/j.devcel.2017.10.033