Thrombomodulin favors leukocyte microvesicle fibrinolytic activity, reduces NETosis and prevents septic shock-induced coagulopathy in rats

BACKGROUND: Septic shock-induced disseminated intravascular coagulation is responsible for increased occurrence of multiple organ dysfunction and mortality. Immunothrombosis-induced coagulopathy may contribute to hypercoagulability. We aimed at determining whether recombinant human thrombomodulin (r...

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Detalles Bibliográficos
Autores principales: Helms, Julie, Clere-Jehl, Raphaël, Bianchini, Elsa, Le Borgne, Pierrick, Burban, Mélanie, Zobairi, Fatiha, Diehl, Jean-Luc, Grunebaum, Lelia, Toti, Florence, Meziani, Ferhat, Borgel, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722785/
https://www.ncbi.nlm.nih.gov/pubmed/29222696
http://dx.doi.org/10.1186/s13613-017-0340-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722785/
https://www.ncbi.nlm.nih.gov/pubmed/29222696
http://dx.doi.org/10.1186/s13613-017-0340-z

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