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Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice

Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Among the family members, the Cib1 and Cib2 genes are expressed in mouse cochlear hair cells, and mutations in th...

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Detalles Bibliográficos
Autores principales: Wang, Yanfei, Li, Jie, Yao, Xuerui, Li, Wei, Du, Haibo, Tang, Mingliang, Xiong, Wei, Chai, Renjie, Xu, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722843/
https://www.ncbi.nlm.nih.gov/pubmed/29255404
http://dx.doi.org/10.3389/fnmol.2017.00401