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Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice

Ancestral environmental exposures to non-mutagenic agents can exert effects in unexposed descendants. This transgenerational inheritance has significant implications for understanding disease etiology. Here we show that exposure of F0 mice to the obesogen tributyltin (TBT) throughout pregnancy and l...

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Detalles Bibliográficos
Autores principales: Chamorro-Garcia, Raquel, Diaz-Castillo, Carlos, Shoucri, Bassem M., Käch, Heidi, Leavitt, Ron, Shioda, Toshi, Blumberg, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722856/
https://www.ncbi.nlm.nih.gov/pubmed/29222412
http://dx.doi.org/10.1038/s41467-017-01944-z