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Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice
Ancestral environmental exposures to non-mutagenic agents can exert effects in unexposed descendants. This transgenerational inheritance has significant implications for understanding disease etiology. Here we show that exposure of F0 mice to the obesogen tributyltin (TBT) throughout pregnancy and l...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722856/ https://www.ncbi.nlm.nih.gov/pubmed/29222412 http://dx.doi.org/10.1038/s41467-017-01944-z |