Structural abnormalities in islets from very young children with cystic fibrosis may contribute to cystic fibrosis-related diabetes

Cystic fibrosis (CF)-related diabetes (CFRD) is thought to result from beta-cell injury due in part to pancreas exocrine damage and lipofibrosis. CFRD pancreata exhibit reduced islet density and altered cellular composition. To investigate a possible etiology, we tested the hypothesis that such chan...

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Detalles Bibliográficos
Autores principales: Bogdani, Marika, Blackman, Scott M., Ridaura, Cecilia, Bellocq, Jean-Pierre, Powers, Alvin C., Aguilar-Bryan, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722914/
https://www.ncbi.nlm.nih.gov/pubmed/29222447
http://dx.doi.org/10.1038/s41598-017-17404-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722914/
https://www.ncbi.nlm.nih.gov/pubmed/29222447
http://dx.doi.org/10.1038/s41598-017-17404-z

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