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Embryonic lethality and defective male germ cell development in mice lacking UTF1

The germ cell lineage is specified early in embryogenesis and undergoes complex developmental programs to generate gametes. Here, we conducted genetic studies to investigate the role of Utf1 (Undifferentiated embryonic cell transcription factor 1) in mouse germ cell development. Utf1 is expressed in...

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Detalles Bibliográficos
Autores principales: Kasowitz, Seth D., Luo, Mengcheng, Ma, Jun, Leu, N. Adrian, Wang, P. Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722945/
https://www.ncbi.nlm.nih.gov/pubmed/29222434
http://dx.doi.org/10.1038/s41598-017-17482-z