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Interferon Potentiates Toll-Like Receptor-Induced Prostaglandin D(2) Production through Positive Feedback Regulation between Signal Transducer and Activators of Transcription 1 and Reactive Oxygen Species
Prostaglandin D(2) (PGD(2)) is a potent lipid mediator that controls inflammation, and its dysregulation has been implicated in diverse inflammatory disorders. Despite significant progress made in understanding the role of PGD(2) as a key regulator of immune responses, the molecular mechanism underl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723016/ https://www.ncbi.nlm.nih.gov/pubmed/29255467 http://dx.doi.org/10.3389/fimmu.2017.01720 |