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Interferon Potentiates Toll-Like Receptor-Induced Prostaglandin D(2) Production through Positive Feedback Regulation between Signal Transducer and Activators of Transcription 1 and Reactive Oxygen Species

Prostaglandin D(2) (PGD(2)) is a potent lipid mediator that controls inflammation, and its dysregulation has been implicated in diverse inflammatory disorders. Despite significant progress made in understanding the role of PGD(2) as a key regulator of immune responses, the molecular mechanism underl...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Yun, Choi, Go-Eun, Yoo, Hyun Ju, Kim, Hun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723016/
https://www.ncbi.nlm.nih.gov/pubmed/29255467
http://dx.doi.org/10.3389/fimmu.2017.01720