Cargando…

A systematic review of test accuracy studies evaluating molecular micro-satellite instability testing for the detection of individuals with lynch syndrome

BACKGROUND: A systematic review was conducted to assess the diagnostic test accuracy of polymerase chain reaction (PCR)-based microsatellite instability (MSI) testing for identifying Lynch syndrome in patients with colorectal cancer (CRC). Unlike previous reviews, this was based on assessing MSI tes...

Descripción completa

Detalles Bibliográficos
Autores principales: Coelho, Helen, Jones-Hughes, Tracey, Snowsill, Tristan, Briscoe, Simon, Huxley, Nicola, Frayling, Ian M., Hyde, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723028/
https://www.ncbi.nlm.nih.gov/pubmed/29221446
http://dx.doi.org/10.1186/s12885-017-3820-5