Skeletal Muscle Fibre-Specific Knockout of p53 Does Not Reduce Mitochondrial Content or Enzyme Activity

Tumour protein 53 (p53) has been implicated in the regulation of mitochondrial biogenesis in skeletal muscle, with whole-body p53 knockout mice displaying impairments in basal mitochondrial content, respiratory capacity, and enzyme activity. This study aimed to determine the effect of skeletal muscl...

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Detalles Bibliográficos
Autores principales: Stocks, Ben, Dent, Jessica R., Joanisse, Sophie, McCurdy, Carrie E., Philp, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723034/
https://www.ncbi.nlm.nih.gov/pubmed/29255419
http://dx.doi.org/10.3389/fphys.2017.00941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723034/
https://www.ncbi.nlm.nih.gov/pubmed/29255419
http://dx.doi.org/10.3389/fphys.2017.00941

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