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Skeletal Muscle Fibre-Specific Knockout of p53 Does Not Reduce Mitochondrial Content or Enzyme Activity

Tumour protein 53 (p53) has been implicated in the regulation of mitochondrial biogenesis in skeletal muscle, with whole-body p53 knockout mice displaying impairments in basal mitochondrial content, respiratory capacity, and enzyme activity. This study aimed to determine the effect of skeletal muscl...

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Detalles Bibliográficos
Autores principales:	Stocks, Ben, Dent, Jessica R., Joanisse, Sophie, McCurdy, Carrie E., Philp, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723034/ https://www.ncbi.nlm.nih.gov/pubmed/29255419 http://dx.doi.org/10.3389/fphys.2017.00941

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