Rolipram, a Selective Phosphodiesterase 4 Inhibitor, Ameliorates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain through Inhibition of Inflammatory Cytokines in the Dorsal Root Ganglion

Chemotherapy-induced neuropathic pain is a significant side effect of chemotherapeutic agents and is the most common reason for stopping chemotherapy. The aim of the present study was to find the major site and mechanisms of action by which rolipram, a selective phosphodiesterase-4 inhibitor, allevi...

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Detalles Bibliográficos
Autores principales: Kim, Hee Kee, Hwang, Seon-Hee, Oh, Elizabeth, Abdi, Salahadin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723089/
https://www.ncbi.nlm.nih.gov/pubmed/29255417
http://dx.doi.org/10.3389/fphar.2017.00885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723089/
https://www.ncbi.nlm.nih.gov/pubmed/29255417
http://dx.doi.org/10.3389/fphar.2017.00885

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