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A screening system to identify transcription factors that induce binding site-directed DNA demethylation

BACKGROUND: DNA methylation is a fundamental epigenetic modification that is involved in many biological systems such as differentiation and disease. We and others recently showed that some transcription factors (TFs) are involved in the site-specific determination of DNA demethylation in a binding...

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Detalles Bibliográficos
Autores principales: Suzuki, Takahiro, Maeda, Shiori, Furuhata, Erina, Shimizu, Yuri, Nishimura, Hajime, Kishima, Mami, Suzuki, Harukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723091/
https://www.ncbi.nlm.nih.gov/pubmed/29221486
http://dx.doi.org/10.1186/s13072-017-0169-6