COMT Val(158)Met Polymorphism Exerts Sex-Dependent Effects on fMRI Measures of Brain Function

Evidence suggests that dopamine levels in the prefrontal cortex (PFC) modulate executive functions. A key regulator of PFC dopamine is catechol-O-methyltransferase (COMT). The activity level of the COMT enzyme are influenced by sex and the Val(158)Met polymorphism (rs4680) of the COMT gene, with mal...

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Detalles Bibliográficos
Autores principales: Elton, Amanda, Smith, Christopher T., Parrish, Michael H., Boettiger, Charlotte A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723646/
https://www.ncbi.nlm.nih.gov/pubmed/29270116
http://dx.doi.org/10.3389/fnhum.2017.00578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723646/
https://www.ncbi.nlm.nih.gov/pubmed/29270116
http://dx.doi.org/10.3389/fnhum.2017.00578

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