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Herpes Simplex Virus 1 Envelope Cholesterol Facilitates Membrane Fusion

Methyl beta-cyclodextrin (MβCD) treatment of herpes simplex virus 1 (HSV-1) reduced envelope cholesterol levels and inhibited viral entry and infectivity in several cell types, regardless of the dependence of entry on endocytosis or low pH. Viral protein composition was similar in MβCD-treated and u...

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Detalles Bibliográficos
Autores principales: Wudiri, George A., Schneider, Seth M., Nicola, Anthony V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723649/
https://www.ncbi.nlm.nih.gov/pubmed/29270154
http://dx.doi.org/10.3389/fmicb.2017.02383