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Circulating Plasmablasts from Chronically Human Immunodeficiency Virus-Infected Individuals Predominantly Produce Polyreactive/Autoreactive Antibodies

Understanding the B-cell response during chronic human immunodeficiency virus (HIV) infection is essential for eliciting broad and potent neutralizing antibodies (Abs). In this study, we analyzed the plasmablast repertoire of chronically HIV-infected individuals in combination with antiretroviral th...

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Detalles Bibliográficos
Autores principales: Liao, Hongyan, Yu, Yangsheng, Li, Song, Yue, Yinshi, Tao, Chuanmin, Su, Kaihong, Zhang, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723652/
https://www.ncbi.nlm.nih.gov/pubmed/29270169
http://dx.doi.org/10.3389/fimmu.2017.01691