Cargando…
Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation
Methylglyoxal (MG) is a metabolite of glucose that may contribute to peripheral neuropathy and pain in diabetic patients. MG increases intracellular calcium in sensory neurons and produces behavioral nociception via the cation channel transient receptor potential ankyrin 1 (TRPA1). However, rigorous...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723675/ https://www.ncbi.nlm.nih.gov/pubmed/29270106 http://dx.doi.org/10.3389/fnins.2017.00679 |