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Towards natural mimetics of metformin and rapamycin

Aging is now at the forefront of major challenges faced globally, creating an immediate need for safe, widescale interventions to reduce the burden of chronic disease and extend human healthspan. Metformin and rapamycin are two FDA-approved mTOR inhibitors proposed for this purpose, exhibiting signi...

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Detalles Bibliográficos
Autores principales: Aliper, Alexander, Jellen, Leslie, Cortese, Franco, Artemov, Artem, Karpinsky-Semper, Darla, Moskalev, Alexey, Swick, Andrew G., Zhavoronkov, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723685/
https://www.ncbi.nlm.nih.gov/pubmed/29165314
http://dx.doi.org/10.18632/aging.101319