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Towards natural mimetics of metformin and rapamycin
Aging is now at the forefront of major challenges faced globally, creating an immediate need for safe, widescale interventions to reduce the burden of chronic disease and extend human healthspan. Metformin and rapamycin are two FDA-approved mTOR inhibitors proposed for this purpose, exhibiting signi...
Autores principales: | Aliper, Alexander, Jellen, Leslie, Cortese, Franco, Artemov, Artem, Karpinsky-Semper, Darla, Moskalev, Alexey, Swick, Andrew G., Zhavoronkov, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723685/ https://www.ncbi.nlm.nih.gov/pubmed/29165314 http://dx.doi.org/10.18632/aging.101319 |
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