Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration

The terminal stages of neuronal degeneration and death in neurodegenerative diseases remain elusive. Autophagy is an essential catabolic process frequently failing in neurodegeneration. Selective autophagy routes have recently emerged, including nucleophagy, defined as degradation of nuclear compone...

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Detalles Bibliográficos
Autores principales: Baron, Olga, Boudi, Adel, Dias, Catarina, Schilling, Michael, Nölle, Anna, Vizcay-Barrena, Gema, Rattray, Ivan, Jungbluth, Heinz, Scheper, Wiep, Fleck, Roland A., Bates, Gillian P., Fanto, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723708/
https://www.ncbi.nlm.nih.gov/pubmed/29174892
http://dx.doi.org/10.1016/j.cub.2017.10.054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723708/
https://www.ncbi.nlm.nih.gov/pubmed/29174892
http://dx.doi.org/10.1016/j.cub.2017.10.054

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