Differential regulation of the Rac1 GTPase–activating protein (GAP) BCR during oxygen/glucose deprivation in hippocampal and cortical neurons

Brain ischemia causes oxygen and glucose deprivation (OGD) in neurons, triggering a cascade of events leading to synaptic accumulation of glutamate. Excessive activation of glutamate receptors causes excitotoxicity and delayed cell death in vulnerable neurons. Following global cerebral ischemia, hip...

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Detalles Bibliográficos
Autores principales: Smith, Katharine R., Rajgor, Dipen, Hanley, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724004/
https://www.ncbi.nlm.nih.gov/pubmed/29046349
http://dx.doi.org/10.1074/jbc.M117.796292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724004/
https://www.ncbi.nlm.nih.gov/pubmed/29046349
http://dx.doi.org/10.1074/jbc.M117.796292

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